Today, multiple techniques are applied for e.g. coating of solid dosage forms with a favourable, sustained release profile, not only for BCS active ingredients with poor solubility in water. Melt coating processes are a popular strategy. The ability of the excipient system to consistently ensure the expected release profile over as long a period as possible is a decisive criterion for successful developments. Up to now, a tendency for polymorphism, the diversity of crystallisation and energy states, has presented a considerable obstacle in the application in the area of lipid-based materials.
This is where IOI Oleo GmbH’s decades of experience and expertise in the development and production of lipid-based excipients comes into play. We have developed a toolbox of excipients that unites the desired properties, highest purity, batch-to-batch consistency and are polymorphic free.