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Pharma Musterbox 2022cr.kea.tongers2025-05-05T13:27:19+02:00

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IMWITOR® 372 P

WITEPSOL® E 85

IMWITOR® 960 K

WITEPSOL® S 58

MIGLYOL® 812 N

IMWITOR® 900 K

WITEPSOL® H 15

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Produkte

Pharma
Personal Care
Nutrition
Technical Application
Basic Oleo

Expertise

Unsere Expertise
Qualitätsmanagement
Nachhaltigkeit
Produktion
Care Studio

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IOI Oleo GmbH
Herrengraben 31
20459 Hamburg

Start

Kontakt
Impressum
Nutzungsbedingungen / Haftungsausschluss
Datenschutzerklärung
AGB
Meldeportal
Distribution Partner Area
Cookie-Zustimmung ändern

Produkte

Pharma
Personal Care
Nutrition
Technical Application
Basic Oleo

Expertise

Unsere Expertise
Qualitätsmanagement
Nachhaltigkeit
Produktion
Care Studio

Über uns

Über uns
Unser Geschäft
Werte
Messen

People & Culture

Stellenangebote
Ausbildung

IOI Oleo GmbH
Herrengraben 31
20459 Hamburg

Messen
Distribution Partner Area
Kontakt
Impressum
Datenschutzerklärung
Nutzungsbedingungen / Haftungsausschluss
AGB
Meldeportal
Cookie-Zustimmung ändern

IOI Oleo GmbH
Herrengraben 31
20459 Hamburg

MIGLYOL® 128

Key Features

Low viscosity, fast spreading non-polar emollient and refatting agent
Vegetable alternative for light petrochemical emollients or silicones (e.g. D5)

Functionalities

Drug Carrier
Emollient

Typical uses / Dosage forms

Topicals

Physico-Chemical Properties / Appearance

Oily liquid
Viscosity mPa*s 20 °C: ~11.0

Chemical Description / Monograph Name:

Cocoyl Caprylocaprate (Ph. Eur.)
non-GMP

MIGLYOL® 829

Key Features

Neutral, stable oil of high viscosity, low spreading superfatting agent
With a density of ~ 1,01 g/ml it acts emulsion stabilizing and allows inverted emulsion

Functionalities

Drug Carrier
Emollient
Superfatting agent

Typical uses / Dosage forms

Topicals
Oral Spray

Physico-Chemical Properties / Appearance

Light yellowish oily liquid
Viscosity mPa*s 20 °C: ~260.0

Chemical Description / Monograph Name:

Caprylic/Capric/Succinic Triglyceride

IMWITOR® 372 P

Key Features

Partly neutralized, ionic, viscosity enhancing, builds structures similar to Lecithin, stable emulsions at pH range 4 to 7
RECOMMENDED CONCENTRATION: 2 – 4% as main emulsifier, 0.5 – 2.0% as co-emulsifier

Functionalities

Emulsifier O/W
Hot melt Coating
Release modifier

Typical uses / Dosage forms

Granules
Tablets
Topicals

Physico-Chemical Properties / Appearance

Flakes
Melting point °C: ~ 62
HLB value: 10-12

Chemical Description / Monograph Name:

GlycerylStearate Citrate

IMWITOR® 600

Key Features

FCC-compliant, for systems of low viscosity, with excellent stability even with high water content
RECOMMENDED CONCENTRATION: 2 to 4 %

Functionalities

Emulsifier W/O emulsions

Typical uses / Dosage forms

Topicals

Physico-Chemical Properties / Appearance

Amber coloured liquid
HLB value: ~ 4

Chemical Description / Monograph Name:

Polyglyceryl-3 Polyricinoleate

IMWITOR® 988

Key Features

Co-Emulsifier and Bioavailability Booster for poorly-watersoluble drugs

Functionalities

Drug Carrier
Solubilizer
Bioavailability Booster

Typical uses / Dosage forms

Capsules
Topicals
Pour-on

Physico-Chemical Properties / Appearance

Clear, oily liquid
Melting point °C: ~ 23
Monoglycerides: ~ 54 %

Chemical Description / Monograph Name:

Glycerol Monocaprylate, Type I (Ph. Eur., USP-NF)

WITEPSOL® E 85

Key Features

It has a melting point above body temperature and is used if active compounds lower the melting point of the main hard fat because of their fat solubility
It is an approved ingredient for use as lipophilic matrix in bio-degradable subcutaneous implants

Functionalities

Drug Carrier
Consistency regulator
Taste masking
Hot Melt Coating

Typical uses / Dosage forms

Suppositories / Ovules
Orals / Tablets
Topicals
Solid Lipid Nanoparticles

Physico-Chemical Properties / Appearance

Pastilles
Melting point °C: 42.0-44.0
Hydroxyl value mg KOH/g: 5-15

Chemical Description / Monograph Name:

Hard Fat, Adeps solidus (Ph. Eur., USP-NF)

MIGLYOL® 840

Key Features

A polar, high spreading emollient with low viscosity
Excellent dispersing and solvent properties, favored for i.m. injectables and pour-on formulations
Very high stability against thermal and oxidative stress, low impurity profile for improved drug quality

Functionalities

Drug Carrier
Emollient
Solubilizer

Typical uses / Dosage forms

Injectables
Topicals
Pour-ons, Spot-ons

Physico-Chemical Properties / Appearance

Oily liquid
Viscosity at 20 °C: ~ 11 mPa·s

Chemical Description / Monograph Name:

Propylene Glycol Dicaprylocaprate (Ph. Eur., USP-NF)

SOFTISAN® 378

Key Features

Refatting and nourishing emollient
Onset of melting at body temperature
Excellent oxidative stability

Functionalities

Drug Carrier
Consistency regulator
Emollient

Typical uses / Dosage forms

Capsules (hard & soft)
Chewable Tablets
Topicals
Oral preparations

Physico-Chemical Properties / Appearance

Semi-solid fat
Melting point °C: ~ 38

Chemical Description / Monograph Name:

Hard Fat, Adeps solidus (Ph. Eur., USP-NF)

IMWITOR® 375

Key Features

Partly neutralized, oil soluble, builds structures similar to Lecithin, stable emulsions at pH range 4 to 7
Suitable for preparation of SMEDDS
Cold processable
RECOMMENDED CONCENTRATION: 1-3% as main emulsifier, 0.5 – 2% as co-emulsifier or solubilizer in anhydrous systems

Functionalities

Emulsifier O/W
Release modifier

Typical uses / Dosage forms

Topicals
SMEDDS

Physico-Chemical Properties / Appearance

Yellow viscous liquid
HLB value: 10-12

Chemical Description / Monograph Name:

Glyceryl Citrate/Lactate/Linoleate/Oleate

IMWITOR® 308

Key Features

Co-emulsifier & penetration enhancer with bacteriostatic properties
Up to 10% of water can be dissolved to clear solution

Functionalities

Drug Carrier
Solubilizer
Bioavailability Booster
Co-Emulsifier O/W
Refatting Agent

Typical uses / Dosage forms

Capsules
Topicals
Oral Liquids
Aerosols

Physico-Chemical Properties / Appearance

Crystalline solid
Melting point °C: 27-33
Monoglycerides: >= 80 %

Chemical Description / Monograph Name:

Glycerol Monocaprylate, Type II (Ph. Eur., USP-NF)

SOFTIGEN® 767

Key Features

Suitable for use in the preparation of SEDDS
Soluble in water and hydrophilic oils (e.g. MCT oil)
Forms micelles from >0,5% of usage concentration and enables clear formulations

Functionalities

Solubilizer
Refatting agent
Bioavailability booster

Typical uses / Dosage forms

Topicals
Refatting aid in disinfactants
Self-Emulsifying Drug delivery systems

Physico-Chemical Properties / Appearance

Clear liquid
HLB value: ~14

Chemical Description / Monograph Name:

Macrogol 6 Glycerol Caprylocaprate (Ph. Eur.)

SOFTISAN® 154

Key Features

Lipophilic matrix for SLN for controlled drug release, similar to Hydrogenated Palm Oil

Functionalities

Drug Carrier
Consistency regulator
Hot melt Coating
Taste masking

Typical uses / Dosage forms

Topicals
Granules
Tablets
Solid Lipid Nanoparticles

Physico-Chemical Properties / Appearance

Flakes
Melting point °C: 53-58

Chemical Description / Monograph Name:

Hydrogenated Palm Oil

MIGLYOL® 8810

Key Features

Polar, fast- spreading light emollient with excellent solvent characteristics
It is a completely saturated, non-oxidizing neutral oil, exhibiting a low allergenic potential and it is non-sensitizing

Functionalities

Drug Carrier
Emollient

Typical uses / Dosage forms

Topicals

Physico-Chemical Properties / Appearance

Oily liquid
Viscosity mPa*s 20 °C: ~13.0

Chemical Description / Monograph Name:

Butylene Glycol Dicaprylate/ Dicaprate

SOFTISAN® 649

Key Features

Semi-solid, vegetable lanolin substitute, adhesive to skin and wet mucous membranes
Waterbinding capacity of ~ 200%
Film former and helps to improve the skin barrier by reducing transepidermal water loss; especially suitable for wound dressing systems and irritated skin
Odorless, thus no effect on formulation sensorics

Functionalities

Film Former
Emollient
Muco-Adhesive

Typical uses / Dosage forms

Topicals
Wound care

Physico-Chemical Properties / Appearance

Off-whiteopaque mass
Melting point °C: ~ 35

Chemical Description / Monograph Name:

Bis-Diglyceryl Polyacyladipate-2

IMWITOR® 960 K

Key Features

Self-Emulsifying GMS with a monoester content of approx. 30%, emulsion stabilizer for rich creams and ointments
RECOMMENDED CONCENTRATION: 2 to 7%

Functionalities

Emulsifier O/W

Typical uses / Dosage forms

Topical

Physico-Chemical Properties / Appearance

Flakes
Melting point °C: 56-61
HLB value: 9-12

Chemical Description / Monograph Name:

Glycerol Monostearate, Self-emulsifying B.P.

IMWITOR® 742

Key Features

Co-Emulsifier and Bioavailability Booster for poorly water-soluble drugs
Defoaming agent
can incorporate up to 10% of water

Functionalities

Drug Carrier
Solubilizer
Bioavailability Booster
Co-Emulsifier O/W
Defoamer

Typical uses / Dosage forms

Capsules
Topicals
Aerosols

Physico-Chemical Properties / Appearance

Liquid to pasty-solid
Melting point °C: ~ 25
HLB value: 5 – 6

Chemical Description / Monograph Name:

Glycerol Monocaprylocaprate, Type I (Ph. Eur., USP-NF)

WITEPSOL® S 58

Key Features

In comparison to other WITEPSOL hard fats the S-family shows increased wetting properties on mucous tissue and hydrophilic compound, incl. aqueous and ethanolic extracts. This functionality makes especially WITEPSOL® S58 the material of choice for vaginal drug delivery.

Functionalities

Drug Carrier

Typical uses / Dosage forms

Ovules
Suppositories

Physico-Chemical Properties / Appearance

Pastilles
Melting point °C: 31,5-33,5°C
Hydroxyl value mg KOH/g: 60-73

Chemical Description / Monograph Name:

Hard Fat + Polyoxyethylene (25) Cetyl/Stearyl Ether + Glyceryl Ricinoleate (stabilized)

DYNASAN® 114

Key Features

A high melting point monoacid lipid for use in modified/sustained release in oral solid dosage matrices and effective lubricant for tablets

Functionalities

Drug Carrier
Consistency Regulator
Taste masking
Hot Melt Coating
Tabletting Lubricant

Typical uses / Dosage forms

Granules
Tablets
Topicals
Solid Lipid Nanoparticles

Physico-Chemical Properties / Appearance

Flakes or powder
Melting point °C: 55-60

Chemical Description / Monograph Name:

Trimyristin

MIGLYOL® 812 N

Key Features

Neutral, stable, penetration enhancer, drug carrier and emollient
Made from renewable, vegetable raw materials
Excellent stability against thermal and oxidative stress
Low impurity profile for improved drug quality, available also as API-Grade

Functionalities

Drug Carrier
Emollient
Solubilizer
Lubricant

Typical uses / Dosage forms

Injectables
Topicals
Capsules
Oral liquids

Physico-Chemical Properties / Appearance

Oily liquid
Viscosity mPa*s 20 °C: ~30.0

Chemical Description / Monograph Name:

Medium-Chain Triglyceride (Ph. Eur., USP-NF)

SOFTISAN® 601

Key Features

Ready-to-use waterfree O/W cream base
Non-sensitive to common APIs like Ketoprofen, Paracetamol, Heparine, Miconazol etc.
Forms stable emulsions

Functionalities

O/W cream base

Typical uses / Dosage forms

Topicals
Wound care

Physico-Chemical Properties / Appearance

Off-white soft pastilles
Melting point °C: 40-45 (melts directly on skin)

Chemical Description / Monograph Name:

Glycerides, C12-C18 Mono- and Di-, Glyceryl Stearate, PEG-4, Polyoxyethylene (25) Cetyl Stearyl Ether, PEG-32, PEG-6, Medium Chain Triglycerides, Glyceryl Ricinoleate (stabilized)

IMWITOR® 900 K

Key Features

Emulsion stabilizer, dispersing agent and consistency enhancer in O/W emulsions
Lipophilic matrix for oral solid dosage forms (granulation, hot melt technique) and suitable for sustained release
RECOMMENDED CONCENTRATION: 1 to 3%

Functionalities

Co-Emulsifier O/W
Hot Melt Coating
SLN
Tablet lubricant

Typical uses / Dosage forms

Topicals
Tablets
Semi-solids

Physico-Chemical Properties / Appearance

Flakes or Powder
Melting point °C: 54-64
HLB value: ~ 3

Chemical Description / Monograph Name:

Glycerol Monostearate 40–55%, Type II (Ph. Eur., USP-NF)

IMWITOR® 948

Key Features

Suitable for W/O and O/W emulsions
Improves penetration of emollients into the stratum corneum and has water-binding capacity, forms gels in excess water
RECOMMENDED CONCENTRATION: 1 to 3%

Functionalities

Co-Emulsifier
Muco-Adhesive

Typical uses / Dosage forms

Topicals

Physico-Chemical Properties / Appearance

Yellowish, liquid to pasty
HLB value: ~3

Chemical Description / Monograph Name:

Glycerol Mono-Oleate 40 (Ph. Eur., USP-NF)

WITEPSOL® H 15

Key Features

The high degree of esterification and triglyceride content give this product precise melting characteristics
Excellent physiological compatibility
Compound for suspension suppositories having a proportion of solid active compounds of less than 25%, compatible with most APIs

Functionalities

Drug Carrier
Consistency regulator
Lubricant

Typical uses / Dosage forms

Suppositories / Ovules
Orals / Tablets
Topicals

Physico-Chemical Properties / Appearance

Pastilles
Melting point °C: 33.5-35.5
Hydroxyl value mg KOH/g: 5-15

Chemical Description / Monograph Name:

Hard Fat, Adeps solidus (Ph. Eur., USP-NF)

DYNASAN® 118

Key Features

A high melting point monoacid lipid suitable for oral and dermal applications
Effective non-ionic substitute for metal soaps of fatty acids in tablet production in low concentrations (~ 0.5%)
No influence on drug release up to a concentration of 1%
From 2 to 5% hydrophobic characteristics of the tablet matrix increase introduce sustained release characteristics Enhances the tablet fracture stability

Functionalities

Drug Carrier
Consistency Regulator
Taste masking
Hot Melt Coating
Tabletting Lubricant

Typical uses / Dosage forms

Granules
Tablets
Topicals
Solid Lipid Nanoparticles
Self-Emulsifying Drug Delivery Systems

Physico-Chemical Properties / Appearance

Flakes or Powder
Melting point °C: 69-73

Chemical Description / Monograph Name:

Glyceryl Tristearate (USP-NF)